人才队伍

姓    名:
丁宝全
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
dingbq(AT)nanoctr.cn

 简历:
 

    丁宝全,2000年毕业于吉林大学化学系获学士学位。20069月在美国纽约大学化学系获博士学位,导师Nadrian C. Seeman 教授。其后在美国劳伦斯伯克利国家试验室进行博士后研究,合作者为 Jeffrey Bokor 教授。200910月到201010月在亚利桑那州立大学作研究助理教授,合作者Hao Yan教授。201011月进入国家纳米科学中心,被评为博士生导师。 

    研究工作包括:1)核酸及多肽等生物大分子自组装体系,包括DNA自组装结构的合理设计及其与多种纳米材料复合结构的可控制备与性能研究。2)可控组装复合生物纳米材料的功能探索,包括药物递送、生物催化及纳米光子电子学等领域的应用。

    课题组主页:http://www.bdinglab.com/

  


 研究领域:
 

生物大分子可控自组装及功能化


 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 

15. S. Liu, Q. Jiang, X. Zhao, R. Zhao, Y. Wang, Y. Wang, J. Liu, Y. Shang, S. Zhao, T. Wu, Y. Zhang, G. Nie, B. Ding*

A DNA nanodevice-based vaccine for cancer immunotherapy

Nature Materials, 2020, doi: 10.1038/s41563-020-0793-6 (https://rdcu.be/b6SOx)

14. Q. Liu, K. Wan, Y. Shang, Z.-G. Wang*, Y. Zhang, L. Dai, C. Wang, H. Wang*, X. Shi, D. Liu, B. Ding*

Cofactor-free oxidase-mimetic nanomaterials from self-assembled histidine-rich peptides

Nature Materials, 2020, doi: 10.1038/s41563-020-00856-6 (https://rdcu.be/cbuT1)

13. Z. Wang, L. Song, Q. Liu, R. Tian, Y. Shang, F. Liu, S. Liu, S. Zhao, Z. Han, J. Sun, Q. Jiang* and B. Ding* 

A tubular DNA nanodevice as a siRNA/chemo-drug co-delivery vehicle for combined cancer therapy

Angew. Chem. Int. Ed., 2020, doi: 10.1002/anie.202009842

12. J. Liu*, X. Lu, T. Wu, X. Wu, L. Han, and B. Ding*

Branched Antisense and siRNA Co-assembled Nanoplatform for Combined Gene Silencing and Tumor Therapy

Angew. Chem. Int. Ed., 2020, doi:10.1002/anie.202011174

11. N. Li, F. Wu, Z. Han, X. Wang, Y. Liu, C. Yi, S. Ye, G. Lu, L. Yu, Z. Nie*, and B. Ding*

Shape Complementarity Modulated Self-assembly of Nanoring and Nanosphere Hetero-nanostructures

J. Am. Chem. Soc., 2020, 142, 11680-11684

10. Y. Shang, N. Li, S. Liu, L. Wang, Z. Wang, Z. Zhang and B. Ding*

Site-specific Synthesis of Silica Nanostructures on DNA Origami Templates

Adv. Mater., 2020, 32, 2000294

9. J. Liu, T. Wu, X. Lu, X. Wu, S. Liu, S. Zhao, X. Xu, B. Ding*

A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery

J. Am. Chem. Soc., 2019, 141, 19032-19037

8. N. Li, Y. Shang, R. Xu, Q. Jiang, J. Liu, L. Wang, Z. Cheng, B. Ding*

Precise Organization of Metal and Metal Oxide Nanoclusters into Arbitrary Patterns on DNA Origami

J. Am. Chem. Soc., 2019, 141, 17968-17972

7. T. Wu, J. Liu, M. Liu, S. Liu, S. Zhao, R. Tian, D. Wei, Y. Liu, Y. Zhao, H. Xiao, B. Ding*

A Nanobody-Conjugated DNA Nanoplatform for Targeted Platinum Drug Delivery

Angew. Chem. Int. Ed., 2019, 58, 14224-14228

6. Q. Jiang, X. Xu, P. Yin, K. Ma, Y. Zhen, P. Duan, Q. Peng*, W. Chen, B. Ding*

Circularly polarized luminescence of achiral cyanine molecules assembled on DNA templates

J. Am. Chem. Soc., 2019, 141, 9490-9494

5. Q. Jiang, S. Zhao, J. Liu, L. Song, Z. Wang, B. Ding*

Rationally designed DNA-based nanocarriers

Advanced Drug Delivery Reviews, 2019, 147, 2-21

4. Q. Jiang, S. Liu, J. Liu, Z. Wang, B. Ding*

Rationally Designed DNA Origami Nanomaterials for Drug Delivery In Vivo

Adv. Mater. 2019 31(45): e1804785, doi: 10.1002.adma.201804785

3. J. Liu, L. Song, S. Liu, S. Zhao, Q. Jiang, B. Ding*

A Tailored DNA Nanoplatform for Synergistic RNAi-/Chemo-Therapy of Multidrug-Resistant Tumors

Angew. Chem. Int. Ed., 2018, 57, 15486-15490

2. P. Zhan, T. Wen, Z. Wang, Y. He, J. Shi, T. Wang, X. Liu, G. Lu, B. Ding*

DNA Origami Directed Assembly of Gold Bowtie Nanoantennas for Single Molecule Surface-Enhanced Raman Scattering

Angew. Chem. Int. Ed., 2018, 57, 2846-2850  

1. S. Li, Q. Jiang, S. Liu, Y. Zhang, Y. Tian, C. Song, J. Wang, Y. Zou, G. Anderson, J. Han, Y. Chang, Y. Liu, C. Zhang, L. Chen, G. Zhou, G. Nie*, H. Yan*, B. Ding*, Y. Zhao*

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

Nature Biotechnology, 2018, 36, 258-264


 承担科研项目情况:
 

基金委面上及优青项目,科技部973子课题