胡志远，中国科学院大学纳米学院教授，博士生导师，中科院特聘核心岗位研究员。复旦大学遗传学本科，美国约翰霍普金斯医学院生物化学博士。在美国系统生物学研究所（ISB），系统生物学奠基人李·胡德（Leroy Hood）教授实验室进行博士后研究，后聘为研究科学家，曾任美国FDA体外诊断医疗器械审评专家。主持了多项科技部、基金委、中科院、市科委项目。 已在《Nature Communications》、《Advanced Materials》、《PNAS》、《J Clin. Invest.》等国际学术期刊上发表论文100余篇，申请发明专利30余项。任中国抗癌协会CTC技术专家委员会组长，中国 CTC 产业联盟理事长，福建医科大学、武汉工程大学的兼职博导，Phenomics杂志编委。

  胡志远课题组网页：http://www.nanoctr.cn/huzhiyuan/ktzjj/

  课题组主要进行纳米转化医学研究，尤其在肿瘤精准医疗方面的应用，研发高灵敏“肿瘤捕手”(TumorFisher)循环肿瘤细胞（CTC）液体活检技术，应用于乳腺癌、肝癌等恶性肿瘤的早期发现和精准用药。主要研究方向为：1）循环肿瘤细胞的纳米检测；2）CTC单细胞多组学分析。

1.         Fang Z^#, Wang C^#, Yang J^#, Song Z, Xie C, Ji Y, Wang Z, Du X, Zheng Q, Chen C*, Hu Z*, Zhong Y*. Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy. Nat Nanotechnol. 2023. doi: 10.1038/s41565-023-01501-4.

2.         Zhang L, Jiang Z*, Yang X, Qian Y, Wang M, Wu S, Li L, Jia F, Wang Z, Hu Z*, Zhao M*, Tang X, Li G, Shang H, Chen X*, Wang W*. A Totipotent “All-In-One” Peptide Sequentially Blocks Immune Checkpoint and Reverses the Immunosuppressive Tumor Microenvironment. Adv. Mater. 2022, 2207330(1)- 2207330(16).

3.         Sun M, Yao S, Fan L, Fang Z, Miao W, Hu Z*, Wang Z*. Fibroblast Activation Protein-α Responsive Peptide Assembling Prodrug Nanoparticles for Remodeling the Immunosuppressive Microenvironment and Boosting Cancer Immunotherapy. Small. 2021, 2106296(1)- 2106296(11)

4.         Tan Z^#, Yue C^#, Ji S, Zhao C, Jia R, Zhang Y, Liu R, Li D, Yu Q, Li P, Hu Z*, Yang Y*, Xu J*.  Assessment of PD-L1 Expression on Circulating Tumor Cells for Predicting Clinical Outcomes in Patients with Cancer Receiving PD-1/PD-L1 Blockade Therapies. Oncologist. 2021, 25: 1-12

5.         Cong Y^#, Ji L^#, Gao Y, Liu F, Cheng D, Hu Z*, Qiao Z*, and Wang H*. Microenvironment-Induced In Situ Self-Assembly of Polymer–Peptide Conjugates That Attack Solid Tumors Deeply. Angew. Chem. Int. Ed. 2019, 58(14), 4632 –4637

6.         Wang W*, Hu Z*. Targeting Peptide-based Probes for Molecular Imaging and Diagnosis. Adv Mater. 2019,31(45):1804827(1)- 1804827(8)

7.         Yue C, Jiang Y, Li P, Wang Y, Xue J, Li N, Li D, Wang R, Dang Y, Hu Z*, Yang Y*& Xu J*. Dynamic change of PD-L1 expression on circulating tumor cells in advanced solid tumor patients undergoing PD-1 blockade therapy, OncoImmunology. 2018, 7(7): e1438111

8.         Wang W, Ma Z, Zhu S, Wan H, Yue J, Ma H, Ma R, Yang Q, Wang Z, Li Q, Qian Y, Yue C, Wang Y, Fan L, Zhong Y, Zhou Y, Gao H, Ruan J, Hu Z*, Liang Y*, Dai H*. Molecular Cancer Imaging in the Second Near-Infrared Window Using a Renal-Excreted NIR-II Fluorophore-Peptide Probe. Adv Mater. 2018, 30(22): 1800106(1)- 1800106(8)

9.         Zhu L^#, Zhao Z^#, Cheng P, He Z, Cheng Z, Peng J, Wang H, Wang C*, Yang Y*, Hu Z*. Antibody-Mimetic Peptoid Nanosheet for Label-Free Serum-Based Diagnosis of Alzheimer’s Disease. Adv Mater. 2017; 29(30): 1700057(1)- 1700057(7)

10.     Zhong Y, Ma Z, Zhu S, Yue J, Zhang M, Antaris A, Yuan J, Cui R, Wan H, Zhou Y, Wang W, Huang N, Luo J, Hu Z* & Dai H*. Boosting the down-shifting luminescence of rareearth nanocrystals for biological imaging beyond 1500 nm. Nat Commun.  2017; 8(1): 737(1)-737(7)