人才队伍

姓    名:
刘颖
性    别:
职    务:
职    称:
副研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
liuy1(AT)nanoctr.cn

 简历:
 
1999.9—2003.6    南开大学化学专业学士
2003.9—2008.6    北京大学化学生物专业博士
2009.1—2012.1    美国国家癌症研究所博士后
2012.1—2013.5    清华大学医学院博士后
2013.6-今         国家纳米科学中心副研究员

 研究领域:
 
1.纳米材料的生物学效应
2.纳米材料的生物安全标准检测

 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 

1. Liu, Y., Sun, R., Wang, W., Wang, J., Oppenheim, J.J., Chen, L., Zhang, N.*: The involvement of lipid rafts in epidermal growth factor-induced chemotaxis of breast cancer cells.  Mol. Membr. Biol. 24: 91-101, 2007.

2. Liu, Y.#, Wang, B.#, Wang, J., Wan, W., Sun, R., Ma, Y., Zhao, Y., and Zhang, N.*: Down-regulation fo PKCzeta expression inhibits chemotaxis signal transduction in human lung cancer cells.  Lung Cancer, 63: 210-218, 2009.(#co-first author)

3. Liu,Y., Wang, J.,Wu, M., Wan, W., Sun, R., Yang,D. Sun, X., Ma, D., Ying, G., Zhang, N.*: Down-regulation of PDK1 level inhibits chemotaxis and metastasis of human breast cancer cells.Mol. CancerRes.7:944-954, 2009.

4. Yang, Y.#,Liu, Y.#, Yao, X., Huang, J., Mou, H., Gong, W.,Chen, K., Bian, X., Wang J.M.*: Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cellgrowth through the formyl peptide receptor 1.Am J Pathol. 179: 1504-1512, 2011.(#co-first author)

5. Liu, Y., Chen K, Yao, X., Gong, W., Liu, M., Wang, J.M.*: Formyl peptide receptor agonistic peptides. Handbook of biologically active peptides. Immunological and inflammatory peptides. Academic Press. (in press)

6. Liu, Y., Chen K, Wang, C., Gong, W., Yoshimura, T., Liu, M.*, Wang, J.M.*: Cell surface receptor FPR2 promotes anti-tumor host defense by limiting M2 polarization ofmacrophages. Cancer Res. 73: 550-560, 2013.

7. Zhao, C.#, Cai, M.#, Zhang, Y.#,Liu, Y., Sun, R., and Zhang, N.*: Development of a microscopy-based assay for protein kinase Czeta activation in human breast cancer cells.  Anal. Biochem. 362: 8-15, 2007.(#co-first author)

8. Wan, W., Zou, H., Sun, R., Liu, Y., Wang, J., Ma, D., and Zhang, N.*: Investigate the role of PTEN in chemotaxis of human breast cancer cells.  Cell. Signal. 19: 2227-2236, 2007.

9. Wang, J., Wan, W., Sun, R., Liu, Y., Sun, X., Ma, D., and Zhang, N.*: Depletion of Akt2 expression inhibits chemotaxis and metastasis of human breast cancer cells.  Cell. Signal. 20: 1025-1034, 2008.

10. Chen, K., Huang, J., Liu, Y., Gong, W., Cui, Y., Wang, J.M.*: Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglia cells.  J Neuroimmunonol. 213: 69-77, 2009.

11. Chen, K., Le, Y., Liu, Y., Gong, W., Ying, G., Huang, J., Yoshimura, T., Tessarollo, L., Wang, J.M.*: A critical role for the G protein-coupled receptor mFPR2 in airway inflammation and immune responses.  J Immunol. 184: 3331-3335, 2010.

12. Chen, K., Xiang, Y., Yao, X., Liu, Y., Gong, W.,Yoshimura, T., Wang, J.M.*: The active contribution of Toll-like receptors to allergic airway inflammation. Int Immunopharmacol. 11:1391-1398, 2011.

13. Yao, X, Liu, Y., Huang, J., Zhou, Y., Chen, K., Gong, W., Liu, M., Bian, X.W., Wang, J.M.*: The role of chemoattractant receptors in the progression of glioma.   Glioma -Exploring Its Biology and Practical Relevance Intech, ISBN978-953-307-379-8. 13: 285-302, 2011.

14.  Liu, M, Chen, K., Yoshimura, T., Liu, Y., Gong, W., Wang, A.,Gao, J.L., Murphy, P.M,, Wang, J.M.*: Formylpeptide receptors are critical forrapid neutrophil mobilization in hostdefense against Listeria monocytogenes. Scientific Rep. 2:1-7, 2012.

15.  Chen, K, Liu, M., Liu, Y., Yoshimura, T., Shen, W., Le, Y., Durum, S., Gong, W., Wang, C., Gao, J.L., Murphy, P.M., Wang, J.M.*: Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis.J Clin Invest. 123:1694–1704, 2013.

16.  Chen, K., Liu, M., Liu, Y., Wang, C., Yoshimura, T., Gong, W., Le, Y., Tessarollo, L., Wang, J.M.*: Signal relay by CCR2 and formylpeptide receptor-2 (Fpr2) in the recruitment of monocyte-derived dendritic cells in allergic airway inflammation. J Biol Chem. (in press)

 


 承担科研项目情况: