人才队伍

姓    名:
王磊
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
wanglei(AT)nanoctr.cn

 简历:
 

1998,09-2002,07 东北师范大学 化学专业学士

2002,09-2005,07 东北师范大学 分析化学专业硕士

2005,09-2008,08 全北国立大学(韩国) 高分子纳米工学科 博士

2008,08-2009,08 全北国立大学(韩国) Polymer BIN(生物-信息-纳米) Fusion Research Center 博士后

2009,12-2012,02 北京科技大学 材料科学与工程学院讲师

2012,03-2014,03    国家纳米科学中心 纳米生物与安全效应实验室 助理研究员

2014,03-2017,03    国家纳米科学中心 纳米生物与安全效应实验室 副研究员 

2017,03-现在    国家纳米科学中心 纳米生物与安全效应实验室 特聘研究员 

 

 研究领域:
 

基础:/生理条件下微纳结构的组装、转化及其生物学效应

微纳结构分子构筑基元的开发

分子间相互作用、组装结构和形貌的调控

在体纳米结构的表征技术联合

纳米生物学效应的临床导向应用

应用:

   纳米抗菌材料用于骨科内植物抗感染,骨结核治疗;导尿管抗感染;抗菌涂料等

   眼科相关纳米材料,用于后发性白内障的防治,青光眼等;手术辅助医疗器械等

   液晶材料的开发与制备,主要用于液晶显示、药物释放、生物检测、环境、农业领域等


 社会任职:
 

 获奖及荣誉:
 

2008 第一届优秀博士毕业论文奖,全北国立大学高分子纳米工学科

2006 显示技术杰出科学贡献-默克奖 IMID, 2006, 韩国大邱

2006 优秀发表奖-韩国画像学会26届会议, 2006, 韩国首尔


 代表论著:
 

共发表学术论文60余篇,以第一作者或者通讯作者发表论文40余篇,包括Adv. Mater. 3篇),ACS Nano 2篇),Chem. Mater. 1篇),Small 1篇),Nanoscale 2篇),ACS Appl. Mater. Interfaces 2篇),Chem. Commun. 2篇);Adv. Optical Mater. 1篇),J. Mater. Chem.8篇)

 

 

1.      Yao-Xin Lin, Xue-Feng Hu, Yang Zhao, Yu-Juan Gao, Chao Yang, Sheng-Lin Qiao, Jiao Yan, Pei-Pei Yang, Qian Zeng, Zeng-Ying Qiao, Li-Li Li, Jiang-Bing Xie, Si-Quan Zhu, Xiao-Chun Wu, Lei Wang* and Hao Wang*, Intraocular Lens with Amorphous Nanostructured Rim for High-Efficient Eye-Disease Treatment, Adv. Mater. Accepted, 10.1002/adma.201701617.

2.      Pei-Pei Yang, Qiang Luo, Guo-Bin Qi, Yu-Juan Gao, Bing-Nan Li, Jing-Ping Zhang, Lei Wang*, and Hao Wang*, Host Materials Transformable in Tumor Microenvironment for Homing Theranostics, Adv. Mater. 2017, 29, 1605869.

3.      Yao-Xin Lin, Sheng-Lin Qiao, Yi Wang, Ruo-Xin Zhang, Hong-Wei An, Zeng-Ying Qiao, Lei Wang,* and Hao Wang* An in situ Intracellular Self-Assembly Strategy for Quantitative and Temporal Monitoring Autophagy, ACS Nano, 2017, 11 (2), 1826–1839.

4.      Xiao-Xue Hu, Guo-Bin Qi, Yu-Juan Gao, Yao-Xin Lin, Chao Yang, Pei-Pei Yang, Hong-Xun Hao*, Lei Wang*,and Hao Wang*, Artificial Extracellular Matrix Based on Transformable Nanomaterials for High-Efficient Inhibition of Tumor Invasion and Metastasis, ACS Nano, 2017, 11 (4), 4086–4096

5.      Pei-Pei Yang, Yun-Gang Zhai, Yao-Xin Lin, Xiao-Xiao Zhao, Yu-Juan Gao, Yang Yang, An-Ping Xu, Chao Yang, Yong-Sheng Li*, Lei Wang* and Hao Wang*, Janus Nanoparticles with Active Motion by NIR Light Propulsion for High Efficient Enhanced Photothermal Treatment, Small, 2016, 12(39), 5423-5430.

6.      Lei Wang,* Pei-Pei Yang, Xiao-Xiao Zhao and Hao Wang*, Self-assembled nanomaterials for photoacoustic imaging. Nanoscale, 2016, 8(5), 2488-2509.

7.      An-Ping Xu, Pei-Pei Yang, Chao Yang, Yu-Juan Gao, Xiao-Xiao Zhao, Qiang Luo, Li-Zhong Li,* Lei Wang,* and Hao Wang* Bio-inspired metal ions regulate morphological transformation of self-assembled peptide-based nanoparticles, Nanoscale, 2016, 8, 14078-14083.

8.      Sheng-Lin Qiao, Yi Wang, Yao-Xin Lin, Hong-Wei An, Li-Li Li, Lei Wang*, and Hao Wang*, Thermo-Control Over Self-Assembly of Polymeric Bis(pyrene)s on Cell Surfaces for Monitoring and Regulating Receptor Clustering, ACS Appl. Mater. Interfaces, 2016, 8(27), 17016-17022.

9.      Hong-Wei An, Sheng-Lin Qiao, Li-Li Li, Chao Yang, Yao-Xin Lin, Yi Wang, Zeng-Ying Qiao, Lei Wang*, and Hao Wang*, Bioorthogonal Reaction Drives Selective Segmentation of Components from Nanoaggregates for Specific Intracellular Bioimaging, ACS Appl. Mater. Interfaces, 2016, 8 (30), 19202–19207

10. Shuo Chen, Yujuan Gao, Ziquan Cao, Bo Wu, Lei Wang,* Hao Wang,* Zhimin Dang,* and Guojie Wang*, Nanocomposites of Spiropyran-Functionalized Polymers and Upconversion Nanoparticles for Controlled Release Stimulated by Near-Infrared Light and pH, Macromolecules, 2016, 49 (19), 7490–7496.

11. Pei-Pei Yang, Xiao-Xiao Zhao, An-Ping Xu, Lei Wang*, Hao Wang*, Reorganization of Self-Assembled Polymeric Peptides Controlled by Hydrogen Bonding and Hydrophilic/Hydrophobic Balance J. Mater. Chem. B, 2016, 4, 2662-2668.

12. Hong-Wei An, Sheng-Lin Qiao, Chun-Yuan Hou, Yao-Xin Lin, Lei Wang* and Hao Wang* Self-assembled NIR nanovesicles for long-term photoacoustic imaging in vivo, Chem. Commun., 2015, 51, 13488-13491.

13. Zeng-Ying Qiao, Chun-Yuan Hou, Wen-Jing Zhao, Di Zhang, Pei-Pei Yang, Lei Wang* and Hao Wang*., Synthesis of self-reporting polymeric nanoparticles for in situ monitoring endocytic microenvironmental pH, Chem. Commun., 2015, 51, 12609-12612.

14. Pei-Pei Yang, Yang Yang, Yu-Juan Gao, Yi Wang, Ju-Chen Zhang, Yao-Xin Lin, Luru Dai, Junbai Li, Lei Wang,* Hao Wang*, Unprecedentedly High Tissue Penetration Capability of Co-Assembled Nanosystems for Two-Photon Fluorescence Imaging In Vivo, Adv. Optical. Mater., 2015, 3(5), 646-651.

15. Lei Wang, Li-li Li, Yun-shan Fan and Hao Wang*, Host–Guest Supramolecular Nanosystems for Cancer Diagnostics and Therapeutics, Adv. Mater., 2013, 25, 3888–3898.

16. Lei Wang, Wei Li, Jing Lu, Ying-Xi Zhao, Gang Fan, Jing-Ping Zhang* and Hao Wang*, Supramolecular Nano-Aggregates Based on Bis(Pyrene) Derivatives for Lysosome-Targeted Cell Imaging, J. Phys. Chem. C, 2013,117, 26811–26820.

17.Lei Wang, Young-Jin Kim, Myong-Hoon Lee*, Soo-Jin Park, Shiao-Wei Kuo, Stephen Z. D. Cheng, and Kwang-Un Jeong*, Self-Assembly Columnar Superstructure of Swallow-Shaped Asymmetric Tetrathiafulvalene-Based Molecule, Chem. Mater. 2009, 21, 3838–3847.


 承担科研项目情况:
 

作为负责人主持国家自然科学基金面上2项和青年项目1

作为负责人教育部留学回国人员启动基金1

作为负责人主持企业研发项目3

作为研究骨干参与国家重大研发计划、北京市科委前沿技术培育项目等