人才队伍

姓    名:
陈瑞
性    别:
职    务:
职    称:
副研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
chenr@nanoctr.cn

 简历:
 

  1994.09-1998.07   山西大学,生命科学学院,获得学士学位 

  1998.09-2001.07   中国辐射防护研究院,生命科学研究所,获得硕士学位 

  2002.09-2005.07   中国科学院动物研究所,获得博士学位 

  2005.09-2009.08   生命科技公司,研究科学家 

  2009.09-2011.05   清华大学,生命科学学院,博士后 

  2011.06-2015.02   国家纳米科学中心,助理研究员 

  2015.03-至今      国家纳米科学中心,副研究员 


 研究领域:
      纳米毒理学与纳米安全性评价

 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 

  1.Rui Chen, Lili Zhang, Cuicui Ge, Michael T. Tseng, Ru Bai, Ying Qu, Christiane Beer, Herman Autrup, Chunying Chen*, Sub-chronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwall Carbon Nanotubes by Intratracheal Instillation. Chemical Research in Toxicology. 2015, 28 (3):440-450. 

  2.Chen Rui, Xiaofei Shi, Ru Bai, Weiqing Rang, Lingling Huo, Lin Zhao, Dingxin Long, David Y. H. Pui, Chunying Chen*. Airborne Nanoparticle Pollution in a Wire Electrical Discharge Machining Workshop and Potential Health Risks. Aerosol and Air Quality Research. 2015, 15(1):284-294.  

  3.Huo Lingling, Chen Rui, Shi Xiaofei, Bai Ru, Wang Peng, Chang Yanzhong*, Chen Chunying*. High-content screening for assessing nanomaterial toxicity. Journal of Nanoscience and Nanotechnology. 2015, 15:1143-1149.  

  4.Shi Xiaofei, Chen Rui, Huo Lingling, Zhao Lin, Bai Ru, Long Dingxin, Pui David Y. H., Rang Weiqing*, Chen Chunying *. Evaluation of nanoparticles emitted from printers in a clean chamber, a copy center and office rooms: health risks of indoor air quality. Journal of Nanoscience and Nanotechnology. 2015, doi:10.1166/jnn.2015.10314,  

  5.Chen Rui, Huo Lingling, Shi Xiaofei, Bai Ru, Zhang Zhenjiang, Chang Yanzhong*, Chen Chunying*. Endoplasmic reticulum stress induced by zinc oxide nanoparticles is an earlier biomarker for nanotoxicological evaluation. 2014, ACS Nano. 8(3): 2562–2574. 

  6.石小飞, 陈瑞*, 霍玲玲, 赵琳, 白茹, 让蔚清, 陈春英. 打印机使用过程中颗粒物等有害因素释放及其毒理学效应研究进展. 生态毒理学报. 2014, 9(2):339-352.  

  7.Meng Li, Chen Rui, Jiang Aihua, Wang Liming, Wang Peng, Li Chenzhong, Bai Ru, Zhao Yuliang, Autrup Herman, Chen Chunying*. Short multiwall carbon nanotubes promote neuronal differentiation of PC12 cells via up-regulation of the neurotrophin signaling pathway. 2013, Small. 9 (9-10):1786-1798. (Cover story) 

  8.Boyes William K*, Chen Rui, Chen Chunying, Yokel Robert A. The neurotoxic potential of engineered nanomaterials. Neurotoxicology. 2012, 33:(4), 902-910.  

  9.蒋爱华, 陈瑞*, 白茹, 严奉祥, 陈春英. 碳纳米管及其复合材料在神经系统中的应用研究进展. 生物物理学报, 2012, 28 (6): 457-468. 

  10.Chen Rui, Chen Chunying, Chapter 31: Nanotoxicity. In Xie YB ed., 2012. The Nanobiotechnology Handbook, Taylor & Francis Group, 270 Madison Avenue, New York, 599-620. (Chapter) 

  11.Chen Rui, Chang Pingan, Liu Chengyun, Yang Lin, Wu Yijun*. G protein β2 subunit interacts directly with neuropathy target esterase and regulates its activity. The International Journal of Biochemistry & Cell Biology. 2007, 39(1):124-132.  

  12.Chen Rui, Chang Pingan, Long Dingxin, Yang Lin, Wu Yijun*. Down-regulation of neuropathy target esterase by protein kinase C activation with PMA stimulation. Molecular and Cellular Biochemistry. 2007, 302(1-2):179-185. 


 承担科研项目情况:
 

  1.国家自然科学基金,面上项目,纳米氧化锌毒性效应评价及呼吸暴露毒性机理研究,项目负责人。 

  2.国家自然科学基金,面上项目,纳米颗粒呼吸毒性的机理研究及一体化预测模型的建立,项目骨干。