人才队伍

姓    名:
高远
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
gaoy(AT)nanoctr.cn

 简历:
 

  高远,研究员,博士生导师。2005年和2011年分别在南京大学强化部(DII)和布兰戴斯大学取得学士学位和博士学位。2011-2013年在布兰戴斯大学做博士后,导师徐兵教授。2013-2015在美国国立卫生研究院(NIH)和国立标准与技术局(NIST)担任助理研究员。长期从事超分子自组装及生物纳米材料方向的研究,2015年入选中科院“百人计划”加入纳米中心。发表论文40余篇,包括Nature Communications, JACS, Chem. Soc. Rev., ACS Nano等,引用1000+。获得一项美国专利授权。 


 研究领域:
 

  触发类超分子自组装 

  药物递送和可控释放 

  分子影像及癌症诊疗 

  动态光散射,小角中子散射 


 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 

  1.Gao, Y.; Kuang, Y.; Guo,  Z.-F.; Guo, Z. H.; Krauss, I. J.; Xu, B. “Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and A Supramolecular Hydrogel of Taxol Derivative” J. Am. Chem. Soc.2009131, 13576-13577. 

  2.Gao, Y.; Yang, Z. M.; Kuang, Y.; Ma, M. L.; Li, J. Y.; Zhao, F.; Xu, B. “Enzyme-instructed Self-assembly of Peptide Derivatives to Form Nanofibers and Hydrogels” Biopolymers: Peptide Sci.201094, 19-31. 

  3.Gao, Y.; Zhao, F.; Wang, L.; Zhang, Y.; Xu, B. “Small Peptide Nanofibers as the Matrices of Molecular Hydrogels for Mimicking Enzymes and Enhancing the Activity of Enzymes” Chem. Soc. Rev.2010, 39, 3425-3433. 

  4.Gao, Y.; Long, M. J. C.; Shi, J. F.; Hedstrom, L.; Xu, B. “Using supramolecular hydrogels to discover the interactions between proteins and molecular nanofibers of small molecules” Chem. Commun., 2012, 48, 8404-8406. 

  5.Gao, Y.; Shi, J. F.; Yuan, D.; Xu, B. “Imaging enzyme-triggered self-assembly of small molecules inside live cells” Nat. Commun., 2012, 3, 1033. 

  6.Gao, Y.; Berciu, C.; Kuang, Y.; Shi, J. F.; Nicastro, D.; Xu, B. “Probing Nanoscale Self-Assembly of Non-Fluorescent Small Molecules inside Live Mammalian Cells” ACS Nano, 2013, 7, 9055-9063. 

  7.Gao, Y.; Kuang, Y.; Du, X. W.; Zhou, J.; Chandran, P.; Horkay, F.; Xu, B. “Imaging self-assembly dependent spatial distribution of small molecules in cellular environment” Langmuir2013, 29, 15191-15200. 

  8.Huang, P.*, Gao, Y.*, Lin, J., Hu, H., Liao, H., Yan, X., Tang, Y., Jin, A., Song, J., Niu, G., Zhang, G., Horkay, F., Chen, X.* “Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics” ACS Nano, ASAP (Corresponding author) 

  9.Gao, Y.; Kuang, Y.; Xu, B. “Antineoplastic Hydrogels, and Enzyme-Instructed Preparations Thereof“ US Patent 8,658,600, 2014 Feb 25. 


 承担科研项目情况: