人才队伍

姓    名:
李乐乐
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
lilele@nanoctr.cn

 简历:
      李乐乐,研究员,博士生导师,2015年入选中组部“青年千人计划”。2010年于北京大学获博士学位,导师为严纯华院士。2010-2012年在美国伊利诺伊大学香槟分校(UIUC)进行博士后研究,合作导师为Yi Lu教授;2012-2016年麻省理工学院(MIT)和哈佛医学院(HMS)进行博士后研究,合作导师为Robert Langer院士和Daniel S. Kohane教授。20167月加入国家纳米科学中心。目前已在PNASJACSAngew Chem Int EdChem MaterSmall等国际学术期刊上发表学术论文30余篇。

 研究领域:
 

  纳米生物材料 & 纳米生物技术 


 社会任职:
 

 获奖及荣誉:
 

   2015  中组部“青年千人计划” 

   2010  北京大学优秀博士论文 

   2009  钟陈玉兰奖一等奖 


 代表论著:
 

  1. Le-Le Li, Yi Lu*, “Regiospecific Hetero-Assembly of DNA-Functionalized Plasmonic Upconversion Superstructures” J. Am. Chem. Soc. 2015, 137, 5272. 

  2. Lele Li, Rong Tong, Hunghao Chu, Weiping Wang, Robert Langer*, Daniel S. Kohane*, “Aptamer Photoregulation In Vivo” Proc. Natl. Acad. Sci. U.S.A. 2014, 111, 17099.  

  3. Xiaoxia Hu, Ting Wei, Jie Wang, Zi-En Liu, Xinyang Li, Binhao Zhang, Zhihao Li, Lele Li*, Quan Yuan*, “Near-Infrared-Light Mediated Ratiometric Luminescent Sensor for Multimode Visualized Assays of Explosives” Anal. Chem. 2014, 86, 10484.  

  4. Le-Le Li, Peiwen Wu, Kevin Hwang, Yi Lu*, “An Exceptionally Simple Strategy for DNA-Functionalized Up-Conversion Nanoparticles as Biocompatible Agents for Nanoassembly, DNA Delivery, and Imaging” J. Am. Chem. Soc. 2013, 135, 2411. 

  5. Le-Le Li, Mengying Xie, Jie Wang, Xinyang Li, Cheng Wang, Quan Yuan*, Dai-Wen Pang*, Yi Lu*, Weihong Tan, “A Vitamin-responsive Mesoporous Nanocarrier with DNA Aptamer-mediated Cell Targeting” Chem. Commun. 2013, 49, 5823.   

  6. Le-Le Li, Ruobing Zhang, Leilei Yin, Kezhi Zheng, Weiping Qin, Paul R. Selvin, Yi Lu*, “Biomimetic Surface Engineering of Lanthanide-Doped Upconversion Nanoparticles as Versatile Bioprobes” Angew. Chem., Int. Ed. 2012, 51, 6121. 

  7. Le-Le Li, Qian Yin, Jianjun Cheng, Yi Lu*, “Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells” Adv. Healthcare Mater. 2012, 1, 567.  

  8. Le-Le Li, Pinghua Ge, Paul R. Selvin, Yi Lu*, “Direct Detection of Adenosine in Undiluted Serum Using a Luminescent Aptamer Sensor Attached to a Terbium Complex” Anal. Chem. 2012, 84, 7852. 

  9. Le-Le Li, Xue-Feng Fu, Zhen Ren, Ya-Guang Zhao, Wei Feng, Chun-Hua Yan*, “Hierarchical Self-Assembly of Superlattice Hybrids Consisting of Periodic and Alternating Cores of Porphyrin Molecules Separated by Nanoscale Silica Walls” Langmuir 2010, 26, 15730. 

  10. Le-Le Li, Hao Sun, Yan-Chun Bai, Chen-Jie Fang, Chun-Hua Yan*, “Orientational Organization of Organic Semiconductors within Periodic Nanoscale Silica Channels: Modification of Fluorophore Photophysics through Hierarchical Self-Assembly” Chem. Eur. J. 2009, 15, 4716. 

  11. Le-Le Li, Jun Xu, Quan Yuan, Zhen-Xing Li, Wei-Guo Song, Chun-Hua Yan*, “Facile Synthesis of Macrocellular Mesoporous Foam-like Ce-Sn Mixed Oxide with Nanocrystalline Frameworks by Using Triblock Copolymer as Single-TemplateSmall 2009, 5, 2730. 

  12. Le-Le Li, Hao Sun, Chen-Jie Fang, Quan Yuan, Ling-Dong Sun, Chun-Hua Yan*, “Mesostructured Hybrids Containing Potential Donors and Acceptors with Molecular-scale and Meso-scale Segregation and Ordering: Toward the Development of Smart Materials through Hierarchical Self-assembly” Chem. Mater. 2009, 21, 4589. 

  13. Le-Le Li, Wen-Tao Duan, Quan Yuan, Zhen-Xing Li, Hao-Hong Duan, Chun-Hua Yan*, “Hierarchical g-Al2O3 Monoliths with Highly Ordered 2D Hexagonal Mesopores in Macroporous Walls” Chem. Commun. 2009, 6174. 

  14. Le-Le Li, Ling-dong Sun, Ya-Wen Zhang, Chun-Hua Yan*, “Functional-Template Directed Self-Assembly (FTDSA) of Mesostructured Organic–Inorganic Hybrid Materials” Sci. China Ser. B 2009, 52, 1759. 

  15. Le-Le Li, Chen-Jie Fang, Hao Sun, Chun-Hua Yan*, “Hierarchical Self-assembly of pH-Responsive Nanocomposites with Molecular-scale and Mesoscale PeriodicitiesChem. Mater. 2008, 20, 5977. 

  16. Le-Le Li, Wei-Ming Zhang, Quan Yuan, Zhen-Xing Li, Chen-Jie Fang, Ling-Dong Sun, Li-Jun Wan, Chun-Hua Yan*, “Room Temperature Ionic Liquids Assisted Green Synthesis of Nanocrystalline Porous SnO2 and Their Gas Sensor Behaviors” Cryst. Growth Des. 2008, 8, 4165. 

  17. Le-Le Li, Chen-Jie Fang, Quan Yuan, Chun-Hua Yan*, Stabilization of Facial Isomer of Tris(8-hydroxyquinolinate) Aluminum though Confinement in Silica-Surfactant Mesostructures” Appl. Phys. Lett. 2007, 90, 231908. 

  18. Le-Le Li, Hao Sun, Chen-Jie Fang, Jun Xu, Jing-Yi Jin, Chun-Hua Yan*, “Optical Sensors Based on Functionalized Mesoporous Silica SBA-15 for the Detection of Multianalytes (H+, Cu2+) in Water” J. Mater. Chem. 2007, 17, 4492. 


 承担科研项目情况: