人才队伍

姓    名:
季天骄
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
jitj@nanoctr.cn

 简历:
 

  季天骄,国家纳米科学中心研究员,博士生导师。2011年于武汉大学化学基地班专业获学士学位;2016年于中国科学院大学(国家纳米科学中心)获博士学位,并获“2017年度中科院百篇优秀博士论文”奖项,导师为聂广军、赵颖研究员。2016-2020年在哈佛医学院(HMS)波士顿儿童医院及麻省理工学院(MIT)进行博士后研究,合作导师为Daniel S. Kohane教授和Robert Langer教授。20209月加入国家纳米科学中心,组建“药物递送与疼痛管理实验室”。近年来,在Nat. Biomed. Eng., Adv. Mater., Nat. Commun., Angew. Chem. Int. Ed., Nano Today, Nano Lett., ACS Nano, Small, J. Control Release, Biomaterials, ACS Appl. Mater. Interfaces等国际重要学术期刊上发表SCI论文60余篇,申请美国发明专利2项,中国发明专利12, 已授权9项。


 研究领域:
 

微米、纳米药物递送体系用于疾病治疗及疼痛管理。

课题组主页:http://www.nanopain-ji-lab.net/


 社会任职:
 

 获奖及荣誉:
 

2020北京市科学技术奖(自然科学)一等奖”(排名:6/10)

2019波士顿儿童医院The Anesthesia Research Distinguished Trailblazer Award

2017年度中国科学院百篇优秀博士学位论文


 代表论著:
 

1. L. Zhang#, Z. Li#, F. Wang#, Q. Chen, M. Zu, X. Li, J. Wan, X. Yao, X. Lou, Y. Shi, Y. Sheng, M. Wang, J. Yang, X. Wang, Z. Qin*, T. Ji*. Integrin-Enriched Membrane Nanocarrier for the Specific Delivery of RGD‐modified Relaxin Analog to Inhibit Pancreatic Cancer Liver Metastasis through Reversing Hepatic Stellate Cell Activation. Adv. Funct. Mater. 2022, 32, 2208404.

2. T. T. Wheeler#, P. Cao#, M. D. Ghouri, T. Ji*, G. Nie, YL. Zhao*. Nanotechnological strategies for prostate cancer imaging and diagnosis. Sci. China Chem. 2022, 65, 1498-1514.

3. T. Ji#, Y. Li#, X. Deng, A. Y. Rwei, A. Offen, S. Hall, W. Zhang, C. Zhao, M. Mehta, D. S. Kohane*. Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel. Nat. Biomed. Eng. 2021, 5, 1099-1109.

4. D. Liu, B. Deng, Z. Liu, B. Ma, X. Leng, D. Kong, T. Ji*, Lanxia Liu*. Enhanced Antitumor Immune Responses via a Self-Assembled Carrier-Free Nanovaccine. Nano Lett. 2021, 21, 3965-3973.

5. Z. Lian, T. Ji*. Functional Peptide-Based Drug Delivery Systems. J. Mater. Chem. B 2020, 8, 6517-6529. (“Emerging Investigators 2020” invited).

6. T. Ji#, J. Lang#, B. Ning#, F. Qi#, H. Wang, Y. Zhang, R. Zhao, X. Yang, L. Zhang, W. Li, X. Shi, Z. Qin, Y. Zhao, G. Nie. Enhanced Natural Killer Cell Immunotherapy by Rationally Assembling Fc Fragments of Antibodies onto Tumor Membranes. Adv. Mater. 2019, 31, 1804395.

7. T. Ji, D. S. Kohane. Nanoscale systems for local drug delivery. Nano Today 2019, 28, 10765.

8. J. Lang, X. Zhao, Y. Qi, Y. Zhang, X. Han, Y. Ding, J. Guan, T. Ji*, Y. Zhao*, G. Nie*. Reshaping Prostate Tumor Microenvironment to Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem. ACS Nano 2019, 13, 12357-12371.

9. C. Weldon #, T. Ji #, M. T. Nguyen #, A. Rwei, W. Wang, Y. Hao, C. Zhao, M. Mehta, B. Y. Wang, J. Tsui, R. P. Marini, D. S. Kohane*. Nanoscale Bupivacaine Formulations to Enhance the Duration and Safety of Intravenous Regional Anesthesia. ACS Nano 2019, 13, 18-25. 

10. T. Ji#, J. Lang#, J. Wang, R. Cai, Y. Zhang, F. Qi, L. Zhang, X. Zhao, W. Wu, J. Hao, Z. Qin*, Y. Zhao*, G. Nie*. Designing Liposomes to Suppress Extracellular Matrix Expression to Enhance Drug Penetration and Pancreatic Tumor Therapy. ACS Nano 2017, 11, 8668-8678. 

11. T. Ji#, Y. Zhao#, Y. Ding#, J. Wang, R. Zhao, J. Lang, H. Qin, X. Liu, J. Shi, N. Tao, Z. Qin, G. Nie, YL. Zhao*. Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-associated Fibroblasts Activation. Angew. Chem. Int. Ed. 2016, 55, 1050-1055.

12. T. Ji#, Y. Ding#, Y. Zhao*, J. Wang, H. Qin, X. Liu, et al. Peptide Assemblies Integration of Fibroblast Targeting and Cell Penetration Features for Enhanced Antitumor Drugs Delivery. Adv. Mater. 2015, 27, 1865-1873. 

13. T. Ji, Y. Zhao, Y. Ding, G. Nie*, Using Nanomaterials to Target and Regulate the Tumor Microenvironment: Diagnostic and Therapeutic Applications. Adv. Mater. 2013, 25, 3508-3525.

14. T. Ji, Y. Zhao, J. Wang, X. Zheng, Y. Tian, et al. Tumor Fibroblast Specific Activation of Hybrid Ferritin Nanocage-based Optical Probe for Tumor Microenvironment Imaging. Small 2013, 9, 2427-2431.

15. W. Zhang, T. Ji, Y. Li, Y. Zheng, M. Mehta, C. Zhao, A. Liu, D.S. Kohane, Light-triggered release of conventional localanesthetics from a macromolecular prodrugfor on-demand local anesthesia. Nat. Commun. 2020, 11, 2323. 


 承担科研项目情况:
 

  课题组已获得基金委、科技部、中科院、北京市科委项目资助