人才队伍

姓    名:
刘晶
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
jliu@nanoctr.cn

 简历:
 

刘晶,现任国家纳米科学中心研究员,博士生导师。主要基于纳米材料的生物学效应与机制,针对肿瘤和感染等重大疾病的诊断和治疗设计智能纳米药物。近年来,在纳米生物医药领域国际重要期刊发表SCI论文51篇,其中以第一/通讯作者在Angew Chem Int Ed, Adv Mater, Adv Drug Deliv Rev, ACS Nano, Nano Today, Biomaterials, Small等学术期刊发表论文21篇,3篇入选ISI web of knowledge-ESI统计的近十年高引频论文(Highly cited papers: last 10 yearsH因子25。授权发明专利2项。主持国家及省部级项目8项,包括国家自然科学基金2项,北京市自然科学基金重点项1项,中科院先导B、先导C项目骨干等。先后受邀参加 68 届林岛诺贝尔奖获得者大会(全国全学科20名);入选中国科协青年人才托举工程项目(2018);获中国毒理学家资格认证(2019)等。长期担任Nano Today, Biomaterials, Journal of Nanobiotechnology, Exploration, Nanoscale 等国际主流期刊审稿人。


 研究领域:
 

肿瘤与感染性疾病纳米药物的设计与应用

基于磷脂膜的智能药物递送系统

纳米材料的免疫学效应


 社会任职:
 

 获奖及荣誉:
   

 代表论著:
 

(1)Liu, Jing#;Guo,Mengyu#;Chen, Chunying*,Nano-bio interactions:A major principle in the dynamic biological processes of nano-assemblies. Adv Drug Deliv Rev, 2022,186,114318

(2) Liu, Jiaming#; Wang, Aizhu#; Liu, Shihui#; Yang, Ruiqi; Wang, Longwei; Gao, Fene; Zhou, Huige; Yu, Xin*; Liu, Jing*; Chen, Chunying*, Titanium nitride nanozyme for pH-responsive and irradiation enhanced cascade catalytic tumor therapy. Angewandte Chemie International Edition, 2021, 60, 25328-25338 

                                                                                                  

(3) Wang, Longwei#; Li, Bo#; You, Zhen; Wang, Aizhu; Chen, Xuanyu; Song, Gaojing; Yang, Ling; Chen, Dan; Yu, Xin*; Liu, Jing*; Chen, Chunying*, Heterojunction of vertically arrayed MoS2 nanosheet/N-doped reduced graphene oxide enabling a nanozyme for sensitive biomolecule monitoring. Analytical Chemistry, 2021,93, 11123.
                                                    

(4) Guo, Jin-Cheng#; An, Qiao#; Guo, Mengyu#; Xiao, Yating; Li, Bo; Gao, Fene; Wang, Yuqi; Li, Jiayang; Wang, Yaling; Liu, Ying; Meng, Huan; Guo, Jia; Liu, Jing*, Oxugen-independent free radical generation mediated by core-shell magnetic nanocomposites synergizes with immune checkpoint blockade for effective primary and metastatic tumor treatment, Nano Today, 2021, 36, 101024.

                                             

(5) Wang, Longwei#; Gao, Fene#; Wang, Aizhu; Chen, Xuanyu; Li, Hao; Zhang, Xiao; Zheng, Hong; Ji, Rui; Li, Bo; Yu, Xin*; Liu, Jing*; Gu, Zhanjun; Chen, Fulin; Chen, Chunying*, Defect-rich adhesive molybdenum disulfide/rGO vertical heterostructures with enhanced nanozyme activity for smart bacterial killing application, Advanced Materials, 2020, 2005423.

                                    

(6) Guo, Mengyu#; Zhang, Xiao#; Liu, Jing*; Gao, Fene; Zhang, Xiaolei; Hu, Xuhao; Li, Bo; Zhang, Xu; Zhou, Huige; Bai, Ru; Wang, Yaling; Li, Jiayang; Liu, Ying; Gu, Zhanjun; Chen, Chunying, Few-layer bismuthene for checkpoint knockdown enhanced cancer immunotherapy with rapid clearance and sequentially triggered one-for-all strategy, ACS Nano, 2020, 14, 15700-15713.

                                            

(7) Longwei Wang#; Xiao Zhang#; Xin Yu*; Fene Gao; Ziyi Shen; Xiaolei Zhang; Shenguang Ge; Jing Liu*; Zhanjun Gu; Chunying Chen*, An All-Organic Semiconductor C3N4/PDINH Heterostructure with Advanced Antibacterial Photocatalytic Therapy Activity, Advanced Materials, 2019, 1901965.

(8) Liu, Jing#; Zheng, Xiaopeng#; Yan, Liang; Zhou, Liangjun; Tian, Gan; Yin, Wenyan;Wang, Liming; Liu, Ying; Hu, Zhongbo; Gu, Zhanjun*; Chen, Chunying*; Zhao, Yuliang*, Bismuth Sulfide  Nanorods as a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided Photothermal Therapy of Tumor, ACS Nano, 2015, 696-707.

(9) Liu, Jing; Wang, Pengyang; Zhang, Xiao; Wang, Liming*; Wang, Dongliang; Gu, Zhanjun; Tang, Jinglong; Guo, Mengyu; Cao, Mingjing; Zhou, Huige; Liu, Ying*; Chen, Chunying*, Rapid Degradation and High Renal Clearance of Cu3BiS3 Nanodots for Efficient Cancer Diagnosis and Photothermal Therapy in Vivo, ACS Nano, 2016.4, 10, 4587-4598.

(10) Liu, Jing#; Kang, Seung-gu#; Wang, Peng; Wang, Yue; Lv, Xiaonan; Liu, Ying; Wang, Fei; Gu, Zonglin; Yang, Zaixing; Weber, Jeffrey K.; Tao, Ning; Qin, Zhihai; Miao, Qing; Chen, Chunying*; Zhou, Ruhong*; Zhao, Yuliang*, Molecular mechanism of Gd@C82(OH)(22) increasing collagen expression: Implication for encaging tumor, Biomaterials, 2018, 152, 24-36.

(11) Wang, Jing#; Liu, Jing#; Liu, Ying; Wang, Liming; Cao, Mingjing; Ji, Yinglu; Wu, Xiaochun; Xu, Yingying; Bai, Bing; Miao, Qing; Chen, Chunying; Zhao, Yuliang*, Gd-Hybridized Plasmonic Au-Nanocomposites Enhanced Tumor-Interior Drug Permeability in Multimodal Imaging-Guided Therapy, Advanced Materials, 2016, 28, 8950-8958.

(12) Liu, Jing#; Feng, Xiaoyan#; Chen, Zhiyun; Yang, Xiqin; Shen, Ziyi; Guo, Mengyu; Deng, Fangling; Liu, Ying*; Zhang, Heqiu*; Chen, Chunying*, The adjuvant e?ect of C60(OH)22 nanoparticles promoting both humoral and cellular immune responses to HCV recombinant proteins, Materials Science & Engineering C, 2019, 97, 753~759.

(13) Xu, Mengzhen#; Zhang, Can Yang#; Wu, Junguang; Zhou, Huige; Bai, Ru; Shen, Ziyi; Deng, Fangling; Liu, Ying*; Liu, Jing*, PEG-Detachable Polymeric Micelles Self-Assembled from Amphiphilic Copolymers for Tumor-Acidity-Triggered Drug Delivery and Controlled Release, ACS Applied Materials & Interfaces, 2019, 11, 5701-5713.

(14) Guo, Mengyu#; Zhao, Lina#; Liu, Jing#; Wang, Xiaofeng; Yao, Haodong; Chang, Xueling; Liu, Ying; Liu, Jiaming; You, Min; Ren, Jiayu; Wang, Fuhui; Wang, Liming; Wang, Yaling; Liu, Huibiao; Zhao, Yuliang; Cai, Rong; Chen, Chunying, The underlying function and structureal organization of the intracellular protein corona on graphdiyne oxide nanosheet forlocal immunomodulation. Nano Letters, 2021, 21, 6005-6013.

(15) An, Qiao#; Liu, Jing#; Yu, Meng; Wan, Jiaxun; Li, Dian; Wang, Changchun; Chen, Chunying*; Guo, Jia*, Multifunctional Magnetic Gd3+-Based Coordination Polymer Nanoparticles: Combination of Magnetic Resonance and Multispectral Optoacoustic Detections for Tumor-Targeted Imaging in vivo, Small, 2015, 11, 5675~5686.

(16) Xu, Shuai#; Liu, Jing#; Li, Dian; Wang, Liming; Guo, Jia*; Wang, Changchun; Chen, Chunying*, Fe-salphen complexes from intracellular pH-triggered degradation of Fe3O4@Salphen-In-III CPPs for selectively killing cancer cells, Biomaterials, 2014, 35, 1676-1685.

(17) Huang, Sheng#; Liu, Jing#; He, Qian; Chen, Hongli; Cui, Jiabin; Xu, Suying; Zhao, Yuliang; Chen, Chunying*; Wang, Leyu*, Smart Cu1.75S nanocapsules with high and stable photothermal efficiency for NIR photo-triggered drug release, Nano Research, 2015, 8, 4038-4047.

(18) Xiao, Yating#; Liu, Jing#; Guo, Mengyu; Zhou, Huige; Jin, Jun; Liu, Jiaming; Liu, Ying; Zhang, Zhanjun*; Chen, Chunying*, Synergistic Combination Chemotherapy of Carrier-free Celastrol and Doxorubicin Nanocrystals for Overcoming Drug Resistance, Nanoscale, 2018, 10, 12639. 

(19) Yu, Xin*; Zhao, Zhenhuan*; Ren, Na; Liu, Jing*; Sun, Dehui; Ding, Longhua; Liu, Hong*, Top or Bottom, Assembling Modules Determine the Photocatalytic Property of the Sheetlike Nanostructured Hybrid Photocatalyst Composed with Sn3O4 and rGO (GQD), ACS Sustainable Chemistry and Engineering, 2018, 6:11775-11782.

(20) Wang, Song#; Zhang, Jianhua#; Wang, Huan; Yang, Lu; Hong, Shuai; Yu, Bo; Guo, Jincheng; Liu, Jing*; Zhu, Yanbing*, A novel multidimensional signature predicts prognosis in hepatocellular carcinoma patients, Journal of Cellular Physiology, 2018, 1-10.


 承担科研项目情况: